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Journal of Pharmacy Practice
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New Options and Strategies for the Treatment of Urinary Incontinence

Angela K. Treadway, PharmD, BCPS

Department of Pharmacy Practice at Texas Tech Health Sciences Center School of Pharmacy, Dallas/Fort Worth Center, Dallas, Texas, angela.treadway{at}ttuhsc.edu

Ann E. Canales, PharmD, BCPS

Department of Pharmacy Practice at Texas Tech Health Sciences Center School of Pharmacy, Amarillo, Texas

Urinary incontinence is a prevalent, although often unreported, disease within the elderly population, with consequences spanning many aspects of the patient's life. Treatments differ for each subtype of urinary incontinence: urge incontinence, stress incontinence, and incontinence associated with bladder outlet obstruction and lower urinary tract symptoms in men. Limitations in current therapies have negatively affected care for each of these subtypes, particularly in the vulnerable elderly population. An emergence of new treatment options and strategies has created opportunities to optimize care for the general population. These include the use of trospium, darifenacin, solifenacin, and duloxetine as well as the strategic use of antimuscarinic agents in conjunction with alpha adrenergic blockade in men with bladder outlet obstruction. Yet, the literature regarding use of these agents and strategies in the elderly should be carefully evaluated to determine the benefits and the unique risks posed by their use in this vulnerable population.

Key Words: Urinary incontinence • overactive bladder • prostatic hyperplasia • pharmacotherapy • elderly.

Journal of Pharmacy Practice, Vol. 20, No. 1, 29-48 (2007)
DOI: 10.1177/0897190007304836
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